Human ICAM-1/CD54 Alexa Fluor® 750-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: ICAM-1/CD54

Intercellular Adhesion Molecule-1 (ICAM-1) binds the leukocyte integrins LFA-1 and Mac-1. ICAM-1 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1 beta and LPS. Soluble ICAM-1 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface, and is elevated in patients with various inflammatory syndromes such as septic shock, LAD, cancer and transplantation.

Product Datasheets

Related Research Areas

• Adhesion Molecules
• Adhesion Molecules in Angiogenesis
• Adhesion Molecules on Endothelial Cells
• Adhesion Molecules on VSMC
• Adhesive Interactions in Allergy and Asthma
• Adipose-derived Stem Cell Markers
• B Cell Chemotaxis, Migration, and Adhesion
• Dendritic Cell Adhesion and Migration
• Endothelial Cell Markers
• Immunoglobulin Superfamily CAMs
• Mesenchymal Stem Cell Markers
• Monocyte Markers
• Myeloid-derived Suppressor Cells (MDSC)
• Platelet Adhesion Molecules
• Regulatory T Cells (Tregs)
• T Cell Migration/Adhesion