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Human GM2/GD2 Synthase/ B4GALNT1 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB10503S Datasheet
Catalog # Availability Size / Price Qty
FAB10503S-100UG
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Human GM2/GD2 Synthase/ B4GALNT1 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human GM2/GD2 Synthase/ B4GALNT1 in direct ELISAs.
Source
Monoclonal Mouse IgG2b Clone # 1024912
Purification
Protein A or G purified
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human GM2/GD2 Synthase/ B4GALNT1
Ser26-Gln533
Accession # Q00973
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: GM2/GD2 Synthase/ B4GALNT1

B4GALNT1, also known as GM2/GD2 Synthase, is an enzyme involved in the biosynthesis of brain-enriched complex gangliosides GM2, GD2, GT2 and GA2 from GM3, GD3, GT3 and GA3.  This is a critical step in the synthesis of all complex gangliosides enriched in the nervous system of vertebrates.

Long Name
Beta-1,4-N-Acetyl-Galactosaminyltransferase 1
Entrez Gene IDs
2583 (Human); 14421 (Mouse)
Alternate Names
(N-acetylneuraminyl)-galactosylglucosylceramide; B4GALNT1; beta-1,4 N-acetylgalactosaminyltransferase 1; beta1,4GalNAc-T; beta-1,4-N-acetyl-galactosaminyl transferase 1; beta1-4GalNAc-T; GALGT; GALGTEC 2.4.1.92; GALNACT; GalNAc-T; GD2 Synthase; GD2 synthase, GM2 synthase; GM2 Synthase; GM2/GD2 synthase; SIAT2; SPG26; UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1; UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramideN-acetylgalactosaminyltransferase (GalNAc-T)

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