Human FKBP52 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB4095S Datasheet

Catalog #	Availability	Size / Price	Qty
FAB4095S-100UG

All FKBP52 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human FKBP52 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human FKBP52 in Western blots. In Western blots, no cross-reactivity with other FKBP family members is observed.

Source

Monoclonal Rat IgG1 Clone # 425123

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human FKBP52
Met1-Ala459
Accession # Q02790

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: FKBP52

FK506 binding protein, also called FKBP52 and FKBP4, is a peptidyl-prolyl isomerase that catalyzes the transition between cis- and trans- proline residues critical for proper folding of proteins. It associates with HSP90 complexes that are critical for the proper folding of steroid receptors. FKBP52 knockout mice have abnormal reproductive organ development due to disruption of androgen receptor folding; and phosphorylation of FKBP52 at Thr143 seems important for steroid receptor activity.

Long Name

52 kDa FK506 Binding Protein

Entrez Gene IDs

2288 (Human); 14228 (Mouse); 260321 (Rat)

Alternate Names

51 kDa FK506-binding protein; 52 kDa FKBP; 59 kDa immunophilin; EC 5.2.1.8; FK506 binding protein 4, 59kDa; FK506-binding protein 4 (59kD); FK506-binding protein 4; FKBP4; FKBP-4; FKBP51; FKBP52; FKBP-52; FKBP52T-cell FK506-binding protein, 59kD; FKBP59; FKBP5952 kDa FK506-binding protein; HBI; HSP binding immunophilin; Hsp56; HSP-binding immunophilin; Immunophilin FKBP52; p52; p59; peptidyl-prolyl cis-trans isomerase FKBP4; peptidylprolyl cis-trans isomerase; PPIase FKBP4; PPIase; rotamase

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Product Datasheet

Related Research Areas

FAQs

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