Human FAM3B Alexa Fluor® 750-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: FAM3B

FAM3B, also known as Pancreatic-derived factor (PANDER), is a secreted 23 kDa glycoprotein that belongs to the cytokine like-protein family. Members of this family share a four-helix bundle secondary structure similar to that found in many cytokines. As a result of alternative splicing and alternate signal peptide cleavage sites, multiple isoforms are known. FAM3B is expressed by pancreatic islet alpha and beta -cells, reproductive epithelium and a subset of neurons. Recombinant FAM3B has been shown to induce beta -cell apoptosis. The amino acid sequence of mature human FAM3B is 80% identical to that of mature mouse FAM3B.

Product Datasheets

Related Research Areas

• Diabetes
• Diabetes and Obesity Research