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Human Cytosolic Sulfotransferase 1A1/SULT1A1 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB5546S Datasheet
Catalog # Availability Size / Price Qty
FAB5546S-100UG
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Human Cytosolic Sulfotransferase 1A1/SULT1A1 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human Cytosolic Sulfotransferase 1A1/SULT1A1 in direct ELISAs and Western blots. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) SULT1A3 and rhSULT1C4 and approximately 10% cross-reactivity with rhSULT1B1 is observed. No cross-
Source
Monoclonal Mouse IgG1 Clone # 638708
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human Cytosolic Sulfotransferase 1A1/SULT1A1
Glu2-Leu295
Accession # P50225
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 
Immunoprecipitation
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Cytosolic Sulfotransferase 1A1/SULT1A1

Cytosolic Sulfotransferase 1A1 (SULT1A1; also phenol sulfotransferase 1 and thermostable phenol sulfotransferase) is a 35 kDa enzyme belonging to the sulfotransferase 1 family of proteins.  Human SULT1A1 is 295 amino acids (aa) in length.  Human SULT1A1 shares 78% and 73% aa identity with rat and mouse SULT1A1, respectively.  SULT1A1 exists as a homodimer and is expressed in liver, lung, adrenal gland, brain, platelets, and skin.  Functionally, it catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitter.  It also mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could participate as a modulating factor of cancer risk.

Entrez Gene IDs
6817 (Human); 20887 (Mouse); 83783 (Rat)
Alternate Names
Aryl sulfotransferase 1; Cytosolic Sulfotransferase 1A1; EC 2.8.2; EC 2.8.2.1; HAST1/HAST2; Phenol sulfotransferase 1; Phenol-sulfating phenol sulfotransferase 1; P-PST 1; P-PST; PST; ST1A1; ST1A3; STP1 ; STP1MGC5163; STPMGC131921; sulfotransferase 1A1; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; SULT1A1; Thermostable phenol sulfotransferase; thermostable phenol sulfotransferase1; ts-PST; TSPST1

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