Human CD4 Fluorescein-conjugated Antibody

Catalog #: FAB3791F
7 Citations 1 Review Datasheet

Catalog #	Availability	Size / Price	Qty
FAB3791F-100
FAB3791F-025

Detection of CD4 in Human Blood Lymphocytes by Flow Cytometry.

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All CD4 Antibodies

Product Details

Citations (7)

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Reviews (1)

Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CD4 Fluorescein-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human CD4 in direct ELISAs.

Source

Monoclonal Mouse IgG_2A Clone # 11830

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Recombinant Human CD4.
Extracellular Domain
Accession # P01730

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Fluorescein (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of CD4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with (A) Mouse Anti-Human CD4 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB3791F) or (B) Mouse IgG_2AFluorescein Isotype Control (Catalog # IC003F) and Mouse Anti-Human CD3e APC-conjugated Monoclonal Antibody (Catalog # FAB100A). View our protocol for Staining Membrane-associated Proteins.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: CD4

CD4 is a type I membrane glycoprotein belonging to the immunoglobulin superfamily. It is expressed predominantly on thymocytes and a subset of mature T lymphocytes. CD4 functions in collaboration with the T cell receptor in the recognition of peptide antigens that are presented by class II major histocompatibility complexes. CD4 also has been shown to be a coreceptor of HIV entry and specifically binds gp120, the external envelope glycoprotein of HIV.

Entrez Gene IDs

920 (Human); 12504 (Mouse); 24932 (Rat); 403931 (Canine); 101864991 (Cynomolgus Monkey); 493775 (Feline)

Alternate Names

CD_antigen: CD4; CD4 antigen (p55); CD4 antigen; CD4 molecule; CD4 receptor; CD4; CD4mut; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4

Product Datasheets

Product Datasheet

Related Research Areas

Citations for Human CD4 Fluorescein-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

7 Citations: Showing 1 - 7
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Expression of CD200R1 and its Ligand CD200 on T-helper Lymphocytes of Pediatric Patients with Ulcerative Colitis and Crohn's Disease
Authors: Mohamed F. Elshal, Alia M. Aldahlawi, Omar I. Saadah, J Philip Philip McCoy
Clinical Laboratory
Phosphonate-Modified Cellulose Nanocrystals Potentiate the Th1 Polarising Capacity of Monocyte-Derived Dendritic Cells via GABA-B Receptor
Authors: M Beki?, M Vasiljevi?, D Stojanovi?, V Kokol, D Mihajlovi?, D Vu?evi?, P Uskokovi?, M ?oli?, S Tomi?
International Journal of Nanomedicine, 2022-07-23;17(0):3191-3216.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Aerobic exercise in humans mobilizes HSC in an intensity dependent manner
Authors: Gianni Parise
J. Appl. Physiol., 2016-11-23;0(0):jap.00696.201.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Impaired circulating CD4+ LAP+ regulatory T cells in patients with acute coronary syndrome and its mechanistic study.
Authors: Zhu Z, Meng K, Zhong Y, Qi L, Mao X, Yu K, Zhang W, Zhu P, Ren Z, Wu B, Ji Q, Wang X, Zeng Q
PLoS ONE, 2014-02-18;9(2):e88775.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Preferential migration of T regulatory cells induced by IL-16.
Authors: McFadden C, Morgan R, Rahangdale S, Green D, Yamasaki H, Center D, Cruikshank W
J. Immunol., 2007-11-15;179(10):6439-45.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection.
Authors: Fluur C, De Milito A, Fry TJ, Vivar N, Eidsmo L, Atlas A, Federici C, Matarrese P, Logozzi M, Rajnavolgyi E, Mackall CL, Fais S, Chiodi F, Rethi B
J. Immunol., 2007-04-15;178(8):5340-50.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Reduced Dendritic Cells Expressing CD200R1 in Children with Inflammatory Bowel Disease: Correlation with Th17 and Regulatory T Cells
Authors: Mohamed F. Elshal, Alia M. Aldahlawi, Omar I. Saadah, J. Philip McCoy
International Journal of Molecular Sciences