Human CD31/PECAM-1 Biotinylated Antibody Summary
(rh) E‑Selectin, rhICAM-1, -2, -3, rhVCAM-1, or recombinant mouse VCAM-1 is observed.
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: CD31/PECAM-1
The CD31 adhesion molecule, also known as PECAM-1, is expressed in large amounts on endothelial cells at intercellular junctions and on T cell subsets, and to a lesser extent on platelets and most other leukocytes such as monocytes and neutrophils. CD31 binds to itself homotypically, and also to the leukocyte integrin alpha v beta 3 heterotypically. CD31 is required for the transendothelial migration of leukocytes through intercellular junctions of vascular endothelial cells. CD31 has been found in human plasma, and the presence of this circulating isoform is suggested to modulate the transendothelial migration of leukocytes.
Product Datasheets
Citations for Human CD31/PECAM-1 Biotinylated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 4
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Comprehensive epigenome characterization reveals diverse transcriptional regulation across human vascular endothelial cells
Authors: R Nakato, Y Wada, R Nakaki, G Nagae, Y Katou, S Tsutsumi, N Nakajima, H Fukuhara, A Iguchi, T Kohro, Y Kanki, Y Saito, M Kobayashi, A Izumi-Tagu, N Osato, K Tatsuno, A Kamio, Y Hayashi-Ta, H Wada, S Ohta, M Aikawa, H Nakajima, M Nakamura, RC McGee, KW Heppner, T Kawakatsu, M Genno, H Yanase, H Kume, T Senbonmats, Y Homma, S Nishimura, T Mitsuyama, H Aburatani, H Kimura, K Shirahige
Epigenetics Chromatin, 2019-12-19;12(1):77.
Species: Human
Sample Types: Whole Cells
Applications: Cell Purification -
SPIO labeling of endothelial cells using ultrasound and targeted microbubbles at diagnostic pressures
Authors: I Skachkov, Y Luan, ST van Tiel, AFW van der St, N de Jong, MR Bernsen, K Kooiman
PLoS ONE, 2018-09-20;13(9):e0204354.
Species: Human
Sample Types: In Vivo, Whole Cells
Applications: Bioassay -
High-throughput flow cytometry screening of human hepatocellular carcinoma reveals CD146 to be a novel marker of tumor-initiating cells.
Authors: Chen K, Ding A, Ding Y, Ghanekar A
Biochem Biophys Rep, 2016-08-12;8(0):107-113.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Independent, parallel pathways to CXCL10 induction in HCV-infected hepatocytes.
Authors: Brownell J, Wagoner J, Lovelace E, Thirstrup D, Mohar I, Smith W, Giugliano S, Li K, Crispe I, Rosen H, Polyak S
J Hepatol, 2013-06-12;59(4):701-8.
Species: Human
Sample Types: Whole Cells
Applications: Cell Selection
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