Human Carboxypeptidase A2/CPA2 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB28961U Datasheet

Catalog #	Availability	Size / Price	Qty
FAB28961U-100UG

All Carboxypeptidase A2/CPA2 Antibodies

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Human Carboxypeptidase A2/CPA2 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Carboxypeptidase A2/CPA2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) CPA1, rhCPA4, rhCPB1, or rhCPE is observed. Recognizes the pro form (aa 17‑417), but n

Source

Monoclonal Mouse IgG2b Clone # 384023

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Carboxypeptidase A2/CPA2
Leu18-His417
Accession # P48052

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Carboxypeptidase A2/CPA2

Carboxypeptidase A2 encoded by the CPA2 gene cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group (1). It prefers the C-terminal residues with aromatic side chains including Phe, Tyr, and Trp. The deduced amino acid sequence of human CPA2 consists of a signal peptide (aa 1 to 16), a pro region (aa 17 to 112), and a mature chain (aa 113 to 417). The amino acid sequence of human CPA2 is 99.5%, 90%, 87%, 86% and 70% identical to that of chimpanzee, canine, rat, mouse and chicken.

Entrez Gene IDs

1358 (Human)

Alternate Names

carboxypeptidase A2 (pancreatic); Carboxypeptidase A2; CPA2; EC 3.4.17; EC 3.4.17.15