Human Bax Minus C-Terminus Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB846R Datasheet

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FAB846R-100UG

All Bax Antibodies

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Human Bax Minus C-Terminus Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects full-length human Bax in Western blots.

Source

Monoclonal Mouse IgG2b Clone # 127606

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human Bax aa 1-171 Accession # Q07812

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Knockout Validated

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied

Background: Bax

Bax belongs to the Bcl-2 protein family. It forms homodimers and heterodimers with Bcl-2 and functions as an apoptotic activator. Bax interacts with the mitochondrial voltage dependent anion channel and promotes the release of cytochrome c.

Long Name

Bcl Associated X Protein

Entrez Gene IDs

581 (Human); 12028 (Mouse); 24887 (Rat)

Alternate Names

apoptosis regulator BAX; Bax; BCL2-associated X protein; Bcl2-L-4; BCL2L4bcl2-L-4; Bcl-2-like protein 4