Human Aminopeptidase N/CD13 Alexa Fluor® 594-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: Aminopeptidase N/CD13

The human ANPEP gene encodes aminopeptidase N (APN), which is also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161 (1‑3). The deduced amino acid sequence of human APN consists of a short cytoplasmic tail (residues 2 to 8), a transmembrane region (residue 9 to 32), a Ser/Thr rich region and a zinc metalloprotease domain (residues 69 to 966). Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. The roles of APN in many fields, such as neuroscience, hematopoeitic cells, immune system, angiogenesis, cancer and viral infection, have been reviewed (3).

Product Datasheets

Related Research Areas

• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia
• Adipose-derived Stem Cell Markers
• Cancer Stem Cell Markers
• Epithelial Cell Markers and Intracellular Molecules
• Granulocyte Markers
• Infectious Diseases
• Mesenchymal Stem Cell Markers
• Metalloproteases and Regulators
• Monocyte Markers
• Myeloid Lineage Markers
• Renin-Angiotensin System
• Search Bioprocessing Enzymes
• Surface Ectodermal Cells
• Vasoactive Peptide Hormones and Regulators