Human alpha-Fetoprotein/AFP Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB13691V Datasheet

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FAB13691V-100UG

All alpha-Fetoprotein/AFP Antibodies

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Human alpha-Fetoprotein/AFP Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects purified human alpha -Fetoprotein/AFP in Western blots.

Source

Monoclonal Mouse IgG1 Clone # 214107

Purification

Protein A or G purified

Immunogen

Human umbilical cord serum-derived Î±-Fetoprotein/AFP

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: alpha-Fetoprotein/AFP

AFP ( alpha -Fetoprotein) is a 69-73 kDa member of the ALB/AFP/VDB family of proteins. alpha -Fetoprotein is a major plasma protein in the fetus. Its concentration is normally low in the adult except when produced by certain tumors. It is secreted by fetal liver and serves as a carrier molecule for phytoestrogens, heavy metals (Cu and Ni), estrogen and fatty acids. Mature human AFP is 591 amino acids (aa) in length. It contains three albumin domains (aa 19-210, 211-402 and 403-601), plus 15 intrachain disulfide bonds. Mature human AFP shares approximately 66% aa identity with mouse AFP.

Entrez Gene IDs

174 (Human); 11576 (Mouse); 24177 (Rat)

Alternate Names

AFP; Alpha-1-fetoprotein; alpha-fetoglobulin; alpha-Fetoprotein; DSCAM2; FETA; HP; HPAFP