Hemopressin (human, mouse)
Biological Activity
Hemopressin (human, mouse) is a bioactive endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE. Ki values are 27.76, 3.43 and 1.87 μM respectively. Potent hypotensive in vivo. Also acts as a selective CB1 receptor inverse agonist. Displays antinociceptive activity in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme.
Rioli et al.
J.Biol.Chem., 2003;278:8547 -
Hypotensive effects of hemopressin and bradykinin in rabbits, rats and mice. A comparative study.
Blais et al.
Peptides, 2005;26:1317 -
Hemopressin is an inverse agonist of CB1 cannabinoid receptors.
Heimann et al.
Proc.Natl.Acad.Sci.USA, 2007;104:20588
Product Datasheets
Citation for Hemopressin (human, mouse)
The citations listed below are publications that use Tocris products. Selected citations for Hemopressin (human, mouse) include:
1 Citation: Showing 1 - 1
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Glucose metabolism links astroglial mitochondria to cannabinoid effects.
Authors: Jimenez-Blasco Et al.
Nature 2020;583:603
FAQs
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