HaXS8
Chemical Name: N-[[4-[[(2-Amino-9-H-purin-6-yl)oxy]methyl]phenyl]methyl]-2-[4-[(18-chloro-3,6,9,12-tetraoxaoctadec-1yl)oxy]-2,3,5,6-tetrafluorophenoxy]acetamide
Purity: ≥90%
Biological Activity
HaXS8 is a chemical dimerizer that promotes covalent and irreversible HaloTag® and SNAP-tag® substrate dimerization. Cell permeable.HaloTag is a trademark of Promega Corporation, and SNAP-tag is a trademark of New England BioLabs, Inc.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Cell-permeant and photocleavable chemical inducer of dimerization.
Zimmermann et al.
Angew Chem.Int.Ed.Engl., 2014;53:4717 -
Chemical development of intracellular protein heterodimerizers.
Erhart et al.
Chem.Biol., 2013;20:549
Product Datasheets
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