GSK LSD 1 dihydrochloride
Chemical Name: rel-N-[(1R,2S)-2-Phenylcyclopropyl]-4-piperidinamine dihydrochloride
Purity: ≥98%
Biological Activity
GSK LSD 1 dihydrochloride is a potent and selective lysine specific demethylase 1 (LSD1) inhibitor (IC50 = 16 nM). Exhibits >1000-fold selectivity for LSD1 over closely related enzymes including LSD2, MAO-1 and MAO-B. Inhibits cancer cell line growth in vitro.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Product Datasheets
Citation for GSK LSD 1 dihydrochloride
The citations listed below are publications that use Tocris products. Selected citations for GSK LSD 1 dihydrochloride include:
1 Citation: Showing 1 - 1
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Targeting histone demethylase LSD1 for treatment of deficits in autism mouse models.
Authors: Ping Et al.
Mol Psychiatry 2022;27:3355-3366
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