GSK J2
Chemical Name: N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester
Purity: ≥98%
Biological Activity
GSK J2 is an inactive control of GSK J1 (IC50 > 100 μM for inhibition of JMJD3/UTX).Cell permeable ester derivative, GSK J5 and Active Analog also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Kruidenier et al.
Nature, 2012;488:404
Product Datasheets
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