GSK 9027
Chemical Name: N-[4-[1-(4-Fluorophenyl)-1H-indazol-5-yl-3-(trifluoromethyl)phenyl]benzenesulfonamide
Purity: ≥98%
Biological Activity
GSK 9027 is a glucocorticoid receptor agonist (pIC50 = 8). Inhibits production of the proinflammatory mediator IL-6 in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
-
Cytokine-induced loss of glucocorticoid function: effect of kinase inhibitors, long-acting beta(2)-adrenoceptor [corrected] agonist and glucocorticoid receptor ligands.
Rider C, Shah S, Miller-Larsson A, Giembycz M, Newton R
PLoS ONE, 2015;10(1):e0116773. -
Structure guided design of 5-arylindazole glucocorticoid receptor agonists and antagonists.
Yates et al.
J.Med.Chem., 2010;53:4531
Product Datasheets
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for GSK 9027
There are currently no reviews for this product. Be the first to review GSK 9027 and earn rewards!
Have you used GSK 9027?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
