Epoprostenol
Chemical Name: (5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt
Purity: ≥99%
Biological Activity
Epoprostenol is an endogenous prostanoid that is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
PGI2-receptors and molecular mechanisms in platelets and vasculature: state of the art.
Oliva and Nicosia
Pharmacol.Res.Comm., 1987;19:735 -
Comparison of anti-aggregatory effects of PGI2, PGI3 and ilo. on human and rabbit platelets.
Kobzar et al.
Cell.Physiol.Biochem., 2001;11:279
Product Datasheets
Citations for Epoprostenol
The citations listed below are publications that use Tocris products. Selected citations for Epoprostenol include:
2 Citations: Showing 1 - 2
-
Inhibition of profibrotic microRNA-21 affects platelets and their releasate.
Authors: Barwari Et al.
JCI Insight 2018;3
-
Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction.
Authors: Armstrong Et al.
Blood 2015;126:e11
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Epoprostenol
There are currently no reviews for this product. Be the first to review Epoprostenol and earn rewards!
Have you used Epoprostenol?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
