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EN67, phenol

Catalog #: 8003 Datasheet
Catalog # Availability Size / Price Qty
8003/25
EN67, phenol | Degrader Building Blocks
1 Image
Description: UBE2D degrader building block

Chemical Name: N-[[3-(3-Fluoro-4-hydroxyphenyl)-4,5-dihydro-5-isoxazolyl]methyl]-2-propenamide

Purity: ≥95%

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Biological Activity

EN67, phenol is a UBE2D building block. It covalently binds with the allosteric C111 residue on E2 ubiquitin-conjugating enzymes UBE2D. It can be used in targeted protein degraders to degrade neo-substrate targets, including the target proteins BRD4 and androgen receptor, in a UBE2D-dependent manner.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
264.26
Formula:
C13H13FN2O3
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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