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EMD 527040 hydrochloride

Catalog #: 7508 Datasheet
Catalog # Availability Size / Price Qty
7508/5
EMD 527040 hydrochloride | Integrin Receptor Inhibitors
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Description: ανβ6 integrin inhibitor

Chemical Name: N-[1-Oxo-5-(2-pyridinylamino)pentyl]-O-(phenylmethyl)-L-seryl-3-(3,5-dichlorophenyl)-β-alanine hydrochloride

Purity: ≥98%

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Biological Activity

EMD 527040 hydrochloride is an inhibitor of integrin αVβ6. EMD 527040 inhibits binding of αVβ6 to fibronectin and attachment of cells expressing αVβ6 to fibronectin (IC50 values = 6 nM and 1.6 μM, respectively). EMD 527040 shows antifibrotic effects in an animal model of biliary fibrosis and is active in vivo.

Technical Data

M.Wt:
623.96
Formula:
C29H32Cl2N4O5.HCl
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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