Dihydroergotamine mesylate

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Further analysis of the inhibitory effects of dihydroergotamine, cyprohept. and ketanserin on the responses of the rat aorta to 5-hydroxytryptamine.
   Doggrell et al.
   J.Auton.Pharmacol., 1992;12:223
3. Carotid vascular effects of ergot. and dihydroergot. in the pig: no exclusive mediation via 5-HT₁-like receptors.
   de Boer et al.
   Br.J.Pharmacol., 1991;104:183
4. Agonistic properties of alniditan, sumatr. and dihydroergot. on human 5-HT_1B and 5-HT_1D receptors expressed in various mammalian cell lines.
   Lesage et al.
   Br.J.Pharmacol., 1998;123:1655
5. Effects of S9977 and dihydroergot. in an animal experimental model for migraine.
   Villalon et al.
   Pharmacol.Res., 1992;25:125

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