Cordycepin
Chemical Name: 3'-Deoxyadenosine
Purity: ≥98%
Biological Activity
Cordycepin is a nucleoside analog that acts as an anticancer and antifungal agent. Can be converted to 3'-deoxyadenosine triphosphate (3'-dATP), which inhibits ATP-dependent DNA synthesis. Inhibits growth of various tumor cells in vitro.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Cordycepin induces human lung cancer cell apoptosis by inhibiting nitric oxide mediated ERK/Slug signaling pathway
JH Hwang, SJ Park, WG Ko, SM Kang, DB Lee, J Bang, BJ Park, CB Wee, DJ Kim, IS Jang, JH Ko
Am J Cancer Res, 2017;7(3):417-432. -
The synthesis of 3'-dATP and its use as an inhibitor of ATP-dependent DNA synthesis in toluene-treated Escherichia coli.
Gumport and Edelhei et al.
Biochemistry, 1976;15:2804 -
Antifungal activity of 3'-deoxyadenosine (cordycepin).
Sugar and McCaffrey
Antimicrob.Agents Chemother., 1998;42:1424 -
Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotidyl transferase-positive (TdT+) leukemic cells.
Kodama et al.
Biochem.Pharmacol., 2000;59:273
Product Datasheets
Citation for Cordycepin
The citations listed below are publications that use Tocris products. Selected citations for Cordycepin include:
1 Citation: Showing 1 - 1
-
Transcription-replication conflicts underlie sensitivity to PARP inhibitors.
Authors: Petropoulos Et al.
Nature 2024;628:433
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Cordycepin
There are currently no reviews for this product. Be the first to review Cordycepin and earn rewards!
Have you used Cordycepin?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
