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Cisapride

Catalog #: 1695
4 Citations Datasheet
Catalog # Availability Size / Price Qty
1695/10
1695/50
Cisapride | CAS No. 81098-60-4 | 5-HT4 Receptor Agonists
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Description: 5-HT4 agonist; stimulates intestinal ACh release
Alternative Names: R 51619

Chemical Name: (±)-4-Amino-5-chloro-N-[1-[(3R*,4S*)-3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide

Purity: ≥99%

Product Details
Citations (4)
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Biological Activity

Cisapride is a 5-HT4 receptor agonist and gastrokinetic agent. Stimulates intestinal acetylcholine release, possibly via 5-HT4 receptor-dependent and -independent mechanisms, leading to increased intestinal motility.

Technical Data

M.Wt:
465.95
Formula:
C23H29ClFN3O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
81098-60-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Cisapride

The citations listed below are publications that use Tocris products. Selected citations for Cisapride include:

4 Citations: Showing 1 - 4

  1. A hybrid structural approach to analyze ligand binding by the serotonin type 4 receptor (5-HT4).
    Authors: Padayatti Et al.
    Mol Cell Proteomics  2013;12:1259
  2. The Pharmacology of TD-8954, a Potent and Selective 5-HT(4) Receptor Agonist with Gastrointestinal Prokinetic Properties.
    Authors: Beattie Et al.
    Front Pharmacol  2011;2:25
  3. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors.
    Authors: Murray Et al.
    J Neurophysiol  2011;106:925
  4. Modulation of spontaneous firing in rat subthalamic neurons by 5-HT receptor subtypes.
    Authors: Xiang Et al.
    J Neurophysiol  2005;93:1145

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