CHDI 00390576

Catalog #: 6725 Datasheet

Catalog #	Availability	Size / Price	Qty
6725/5

CHDI 00390576 | CAS No. 1629729-98-1 | Histone Deacetylase Inhibitors

1 Image

Description: Potent and selective class IIa HDAC inhibitor; brain penetrant

Chemical Name: 2-(2-Fluorophenyl)-N-hydroxy-2-(4-(5-(trifluoromethyl)pyrimidin-2-yl)phenyl)acetamide

Purity: ≥98%

View All Products for Histone Deacetylase Inhibitors

Product Details

Reviews

Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

CHDI 00390576 is a potent and selective class IIa histone deacetylase (HDAC) inhibitor (IC₅₀ values are 31, 50, 54 and 60 nM for HDAC7, HDAC9, HDAC4 and HDAC5, respectively). Displays >100-fold selectivity for class IIa HDACs over other HDACs. Brain penetrant.

Technical Data

M.Wt:

391.32

Formula:

C₁₉H₁₃F₄N₃O₂

Solubility:

Soluble to 100 mM in DMSO and to 100 mM in ethanol

Purity:

≥98%

Storage:

Store at -20°C

CAS No:

1629729-98-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:

Sold under license from CHDI Foundation

Background References

Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor.
Luckhurst et al.
Bioorg.Med.Chem.Lett., 2019;29:83

Product Datasheets

COA view current batch

Or select another batch:

View Batch

SDS

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for CHDI 00390576

There are currently no reviews for this product. Be the first to review CHDI 00390576 and earn rewards!

Have you used CHDI 00390576?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.