CA 074

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability
   
   PLoS Pathog, 2016;12(7):e1005738.
2. Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release
   C Szot, S Saha, XM Zhang, Z Zhu, MB Hilton, K Morris, S Seaman, JM Dunleavey, KS Hsu, GJ Yu, H Morris, DA Swing, DC Haines, Y Wang, J Hwang, Y Feng, D Welsch, G DeCrescenz, A Chaudhary, E Zudaire, DS Dimitrov, B St Croix
   J. Clin. Invest., 2018;0(0):.
3. Voltage-gated sodium channel activity promotes cysteine cathepsin-dependent invasiveness and colony growth of human cancer cells.
   Gillet et al.
   J.Biol.Chem., 2009;284:8680
4. Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo.
   Towatari et al.
   FEBS Lett., 1991;280:311
5. Cathepsin B inhibition limits bone metastasis in breast cancer.
   Withana N, Blum G, Sameni M, Slaney C, Anbalagan A, Olive M, Bidwell B, Edgington L, Wang L, Moin K, Sloane B, Anderson R, Bogyo M, Parker B
   Cancer Res, 2012-01-19;72(5):1199-209.

Product Datasheets