C-Laurdan
Chemical Name: N-Methyl-N-[6-(1-oxododecyl)-2-naphthalenyl]glycine
Purity: ≥95%
Biological Activity
Key information: C-Laurdan is a polarity-sensitive lipid membrane probe.Used for: lipid raft imaging and cell membrane imaging.
Application: One and two-photon microscopy for membrane polarity.
Properties and Photophysical Data: C-laurdan carry a carboxylic group which can be partially ionized which contributes to its good water solubility and fast membrane incorporation. Two photon excitation spectra = 780 nm. One photon excitation and emission maxima (λ) are 348 nm and 423 nm, respectively; quantum yield = 0.43; extinction coefficient = 12,200 M-1cm-1.
Optical Data for C-Laurdan
| Emission Color | Blue |
|---|---|
| λabs | 348 nm |
| λem | 423 nm |
| Extinction Coefficient (ε) | 12200 M-1cm-1 |
| Quantum Yield (φ) | 0.43 |
| Application | One and Two-photon Microscopy for Membrane Polarity |
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectral Viewer
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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A two-photon fluorescent probe for lipid raft imaging: C-laurdan.
Kim et al.
Chembiochem, 2007;8:553 -
Will C-Laurdan dethrone Laurdan in fluorescent solvent relaxation techniques for lipid membrane studies?
Barucha-Kraszewska et al.
Langmuir, 2013;29:1174 -
Characterization of M-laurdan, a versatile probe to explore order in lipid membranes.
Mazeres et al.
F1000Res., 2014;3:172
Product Datasheets
Citation for C-Laurdan
The citations listed below are publications that use Tocris products. Selected citations for C-Laurdan include:
1 Citation: Showing 1 - 1
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Shortening of membrane lipid acyl chains compensates for phosphatidylcholine deficiency in choline-auxotroph yeast.
Authors: Muriel Et al.
EMBO J 2021;40:e107966
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