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BL660-NO

Catalog #: 7753 Datasheet
Catalog # Availability Size / Price Qty
7753/5
BL660-NO | Bioluminescent Substrates
1 Image
Description: Nitric oxide activity-based sensing NIR bioluminescent probe

Chemical Name: N-(2-Aminophenyl)-2-((1E,3E)-4-(4-(diethylamino)phenyl)buta-1,3-dien-1-yl)-4,5-dihydrothiazole-4-carboxamide

Purity: ≥90%

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Biological Activity

BL660-NO is an activity-based sensing (ABS) bioluminescent probe for near-infrared red (NIR) detection of nitric oxide (NO). BL660-NO is suitable for in vitro, live cell and deep tissue imaging. Used to visualize endogenous NO in vitro, and in murine models of liver and breast cancer. Used to investigate the effect of diet on tumor microenvironment (TME) in mice.

This product is a scalemic mixture of (S) and (R) enantiomers in which (S) is predominant. The exact ratio is batch specific and is expressed as an enantiomeric excess (e.e.) on the Certificate of Analysis.

Technical Data

M.Wt:
420.58
Formula:
C24H28N4OS
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥90%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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