BDY FL Lenalidomide

Catalog #: 7857 Datasheet
Catalog # Availability Size / Price Qty
7857/2
BDY FL Lenalidomide | Fluorescent Ligands
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Description: Fluorescent cereblon ligand

Chemical Name: 3-(5,5-Difluoro-7,9-dimethyl-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-N-(6-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)hexyl)propanamide

Purity: ≥95%

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Biological Activity

BDY FL Lenalidomide is a fluorescent cereblon ligand. It can be used in time-resolved fluorescence resonance energy-transfer (TR-FRET) cereblon binding assays for PROTAC® Degrader development. This assay is highly sensitive, selective, and stable. Excitation and emission maxima (λ) are 506 and 508 nm, respectively.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Optical Data for BDY FL Lenalidomide

BDY FL Lenalidomide Dye Spectra
Emission Color Green
λabs 506 nm
λem 508 nm
Closest Laser line 488 nm
Cell Permeable Yes
Application TR-FRET and FP Assays
Alternative For BDY FL Thalidomide

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Technical Data

M.Wt:
632.52
Formula:
C33H39BF2N6O4
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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