ATPγS tetralithium salt
Chemical Name: Adenosine-5'-(γ-thio)-triphosphate tetralithium salt
Purity: ≥85%
Biological Activity
ATPγS tetralithium salt is a P2 purinergic receptor agonist. Nonhydrolyzable analog of ATP (Cat. No. 3245).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Nutritional state-dependent ghrelin activation of vasopressin neurons via retrograde trans-neuronal-glial stimulation of excitatory GABA circuits.
Haam J, Halmos K, Di S, Tasker J
J Neurosci, 2014;34(18):6201-13. -
Adenosine 5'-O-(3-thio)triphosphate (ATPgammaS) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor elF4A.
Peck and Herschlag
RNA, 2003;9:1180 -
The structure of recA protein-DNA filaments. 2 recA protein monomers unwind 17 base pairs of DNA by 11.5 degrees/base pair in the presence of adenosine 5'-O-(3-thiotriphosphate).
Chrysogelos et al.
J.Biol.Chem., 1983;258:12624 -
Pharmacological characterization of heterologously expressed ATP-gated cation channels (P2X purinoceptors).
Evans et al.
Mol.Pharmacol., 1995;48:178
Product Datasheets
Citations for ATPγS tetralithium salt
The citations listed below are publications that use Tocris products. Selected citations for ATPγS tetralithium salt include:
7 Citations: Showing 1 - 7
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Differential Regulation of ATP- and UTP-Evoked Prostaglandin E2 and IL-6 Production from Human Airway Epithelial Cells.
Authors: Timothy S Et al.
J Immunol 2021;207:1275-1287
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Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independent manner.
Authors: Jean-Michel Et al.
Elife 2021;10
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A Photo-clickable ATP-Mimetic Reveals Nucleotide Interactors in the Membrane Proteome.
Authors: Ke Et al.
Cell Chem Biol 2020;27:1073-1083.e12
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Extracellular ATP Increases Glucose Metabolism in Skeletal Muscle Cells in a P2 Receptor Dependent Manner but Does Not Contribute to Palmitate-Induced Insulin Resistance
Authors: Miguel Cruz & Beall Et al.
Front Physiol 2020;11
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Wound-induced Ca2+ wave propagates through a simple release and diffusion mechanism.
Authors: Handly & Wollman
Mol Biol Cell 2017;28:1457
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Extracellular ATP protects endothelial cells against DNA damage.
Authors: Aho Et al.
Purinergic Signal 2016;12:575
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Osmotic surveillance mediates rapid wound closure through nucleotide release.
Authors: Gault Et al.
J Cell Biol 2014;207:767
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