ATN 161

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Anti-invasive, antitumorigenic, and antimetastatic activities of the PHSCN sequence in prostate carcinoma.
   Livant et al.
   Cancer Res., 2000;60:309
2. A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo.
   Khalili et al.
   Mol.Cancer Ther., 2006;5:2271
3. The exosome-mediated autocrine and paracrine actions of plasma gelsolin in ovarian cancer chemoresistance
   M Asare-Were, K Nakka, A Reunov, CT Chiu, WT Lee, MR Abedini, PW Wang, DB Shieh, FJ Dilworth, E Carmona, T Le, AM Mes-Masson, D Burger, BK Tsang
   Oncogene, 2019;0(0):.
4. Inhibition of integrin α5β1 function with a small peptide (ATN-161) plus continuous 5-FU infusion reduces colorectal liver metastases and improves survival in mice.
   Stoeltzing et al.
   Int.J.Cancer., 2003;104:496

Product Datasheets