Aripiprazole
Chemical Name: 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
Purity: ≥99%
Biological Activity
Aripiprazole is a high affinity dopamine D2 and 5-HT1A receptor partial agonist (Ki values are ~1.64 and 5.59 nM respectively). Also 5-HT2A antagonist (Ki = 8.7 nM). Suppresses morphine-induced emesis in vivo. Atypical antipsychotic.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Aripiprazole: a novel atypical antipsychotic drug with a uniquely robust pharmacology.
Davies et al.
CNS Drug Rev., 2004;10:317 -
Usefulness of the DA system-stabilizer aripipr. for reducing morphine-induced emesis.
Shiokawa et al.
Eur.J.Pharmacol., 2007;570:108
Product Datasheets
Citation for Aripiprazole
The citations listed below are publications that use Tocris products. Selected citations for Aripiprazole include:
1 Citation: Showing 1 - 1
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Spinal Inhibition of GABAB Receptors by the Extracellular Matrix Protein Fibulin-2 in Neuropathic Rats.
Authors: Marc Et al.
Front Cell Neurosci 2020;14:214
FAQs
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