α-Estradiol
Chemical Name: (17α)-Estra-1,3,5(10)-triene-3,17-diol
Purity: ≥97%
Biological Activity
α-Estradiol is an endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).β-Estradiol also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β.
Kuiper et al.
Endocrinology, 1997;138:863 -
ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury.
Toran-Allerand et al.
J.Neurosci., 2002;22:8391
Product Datasheets
Citations for α-Estradiol
The citations listed below are publications that use Tocris products. Selected citations for α-Estradiol include:
3 Citations: Showing 1 - 3
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Endogenous 17β-OE is required for activity-dependent long-term potentiation in the striatum: interaction with the DArgic system.
Authors: Tozzi Et al.
Front Cell Neurosci 2015;9:192
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Robust network structure of the Sln1-Ypd1-Ssk1 three-component phospho-relay prevents unintended activation of the HOG MAPK pathway in Saccharomyces cerevisiae.
Authors: Dexter Et al.
Sci Rep 2015;9:17
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Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway.
Authors: McIsaac Et al.
Mol Biol Cell 2012;23:2993
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