Home / Degrader Building Blocks / A 410099.1 amide-PEG4-amine

A 410099.1 amide-PEG4-amine

Catalog #: 7220 Datasheet
Catalog # Availability Size / Price Qty
7220/25
A 410099.1 amide-PEG4-amine | CAS No. 2446474-10-6 | Degrader Building Blocks
1 Image
Description: IAP ligand with PEG linker and terminal amine for onward chemistry

Chemical Name: tert-Butyl ((S)-1-(((S)-2-((2S,4S)-4-(14-amino-3,6,9,12-tetraoxatetradecanamido)-2-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-1-yl)-1-cyclohexyl-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate

Purity: ≥95%

Product Details
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

A 410099.1 amide-PEG4-amine is a functionalized IAP ligand for PROTAC® research and development; incorporates an IAP ligand plus an amide-PEG4 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
817.02
Formula:
C42H68N6O10
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2446474-10-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. PROTAC-mediated degradation of Bruton's tyrosine kinase is inhibited by covalent binding.
    Tinworth et al.
    ACS Chem.Biol., 2019;14:342

Product Datasheets

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for A 410099.1 amide-PEG4-amine

There are currently no reviews for this product. Be the first to review A 410099.1 amide-PEG4-amine and earn rewards!

Have you used A 410099.1 amide-PEG4-amine?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.